Tuesday, August 25, 2020

Effects of Earthquake Essay

Essential impacts are the quick harm brought about by the shake, for example, falling structures, streets and scaffolds, which may execute numerous individuals. Those fortunate enough to endure can experience the ill effects of stun and frenzy. Auxiliary impacts are the eventual outcomes of the seismic tremor, for example, fires, tsunamis, avalanches and ailment. Fire †quakes obliterate gas funnels and electric links, making fires spread. Broken water mains forestall the Fires being stifled. Flames spread rapidly in urban communities, particularly in low quality lodging territories where wooden structures are normal. Tidal waves †a seismic tremor on the ocean bottom or near the coast may cause gigantic waves. Avalanches †seismic tremors regularly cause avalanches, particularly in steep stream valleys and zones of feeble rocks. Ailment and starvation †new water supplies are regularly cut off causing typhoid and cholera. Absence of asylum and food causes a lot of torment. soil liquefaction when soils with a high water content are brutally shaken they lose their mechanical quality and carry on like a liquid thus structures can actually sink. Incredible clasp 2011 Japan Tsunamis Super tidal wave brought about by a surprising margin July ninth 1958 Clarification Blueprint causes A tidal wave can be produced when dangerous plate limits unexpectedly move and vertically uproot the overlying water. It is far-fetched that they can shape at valuable or moderate plate limits. This is on the grounds that valuable or preservationist limits don't by and large upset the vertical removal of the water section. Subduction zone related tremors produce most everything being equal. Torrents have a little wave stature seaward, and an extremely long frequency (regularly several kilometers in length), which is the reason they for the most part pass unnoticed adrift, framing just a slight swell ordinarily around 300 mm over the ordinary ocean surface. also, they travel rapidly at speeds more than 700 km/h. They develop in tallness when they reach shallower water.

Saturday, August 22, 2020

You Have read about HITECH Act,HIPAA,ARRA,and electronic Essay

You Have found out about HITECH Act,HIPAA,ARRA,and electronic signatures.Summarize the intentof one of these laws and its effect on your training - Essay Example Such HIT incorporates electronic wellbeing records and secure and private trade of electronic wellbeing data (McGonigle and Mastrian, 2015). McGonigle and Mastrian (2015) plots that, in caption D, the HITECH Act locations and states the security and protection concerns connected with the electronic transmission or dispersion of wellbeing data. To a limited extent, the Act has various arrangements that strengthen the crook and common implementation of the HIPAA rules. These arrangements greatly affect wellbeing arrangement and general social insurance. As a records nurture specialist and official, I am enormously impacted with the HITECH Act. I am engaged with various trades of human services records and data. My work must be discrete and private to guarantee security of social insurance data and patients’ wellbeing records. Through the Act, I currently practice more alert and care to guarantee that the electronic wellbeing data and documents don't land in wrong hands. In its segment, there are punishments for infringement of the Act. The guidelines and punishments guarantee that professionals, especially in wellbeing records, carefully do their work steadily to guarantee and upgrade the security and security of wellbeing data and patients’ wellbeing records (McGonigle and Mastrian,

Tuesday, August 4, 2020

Applying for Financial Aid Its FAFSA Time! COLUMBIA UNIVERSITY - SIPA Admissions Blog

Applying for Financial Aid It’s FAFSA Time! COLUMBIA UNIVERSITY - SIPA Admissions Blog Applying for financial aid doesn’t involve too many steps. Some of you may want to consider financing part of your costs through student loans or work study.   If so, you will need to complete the 2013/14 Free Application for Federal Student Aid, commonly known as the FAFSA.   To do so, go to www.fafsa.gov.     The information collected on the FAFSA will be used by the SIPA Financial Aid Office to determine your eligibility for student loans available from the federal government and possible work study jobs. If you completed the FAFSA as an undergraduate, you’ll be familiar with the process, although as a graduate student, no parental information is necessary.    If you have a PIN number that you used as an undergraduate, use the same one.   If have never completed a FAFSA before, you will need a PIN in order to complete the FAFSA; you must go to www.pin.ed.gov, which is linked from www.fafsa.gov. When you complete the FAFSA, designate Columbia University as the recipient with our school code number, 002707, in Step 6 of the FAFSA. Do not wait until you have received an admission decision to complete your FAFSA.   While there is no absolute deadline approaching, you should complete the FAFSA as soon as possible; we recommend that you do so by March 1 for a timely review.   Also be aware that this is an annual form, and you will need to complete the 2014/15 FAFSA for your second year should you wish to borrow or be considered for a work study position.   If you are only interested in SIPA scholarships or assistantships and do not wish to borrow loans, you do not need to complete the FAFSA. The FAFSA is a lengthy form that collects a lot of information.   If you are completing the FAFSA for the first time, it can be confusing.   If you have any questions or need any assistance, contact us at 212-854-6216 or email us at sipa_finaid@columbia.edu. Note: Do not complete a FAFSA if you are an international student; it is only used to determine eligibility for student loans and Work Study available to US citizens, permanent residents and political refugees.

Saturday, May 23, 2020

The Origins of Memorial Day

Memorial Day is celebrated in the United States each May to remember and honor military men and women who died while serving in the nations armed forces. This differs from Veterans Day, which is celebrated in September to honor everyone who served in the U.S. military, whether or not they died in service. From 1868 through 1970, Memorial Day was celebrated on May 30th each year. Since then, the official national Memorial Day holiday is traditionally celebrated on the last Monday in May. Origins of Memorial Day On May 5, 1868, three years after the end of the Civil War, Commander in Chief John A. Logan of the Grand Army of the Republic (GAR)—an organization of former Union soldiers and sailors—established Decoration Day as a time for the nation to decorate the graves of the war dead with flowers. The first large observance was held that year at Arlington National Cemetery, across the Potomac River from Washington, D.C. The cemetery already held the remains of 20,000 Union dead and several hundred Confederate dead.  Presided over by General and Mrs. Ulysses S. Grant and other Washington officials, the Memorial Day ceremonies centered around the mourning-draped veranda of the Arlington mansion, once the home of General Robert E. Lee. After speeches, children from the Soldiers and Sailors Orphan Home and members of the GAR made their way through the cemetery, strewing flowers on both Union and Confederate graves, reciting prayers and singing hymns. Was Decoration Day Really the First Memorial Day? While General John A. Logan credited his wife, Mary Logan, with the suggestion for the Decoration Day commemoration, local springtime tributes to the Civil War dead had previously taken place. One of the first occurred in Columbus, Mississippi, on April 25, 1866, when a group of women visited a cemetery to decorate the graves of Confederate soldiers who had fallen in battle at Shiloh. Nearby were the graves of Union soldiers, neglected because they were the enemy. Disturbed at the sight of the bare graves, the women placed some of their flowers on those graves, as well.Today cities in the North and the South claim to be the birthplace of Memorial Day between 1864 and 1866. Both Macon and Columbus, Georgia, claim the title, as well as Richmond, Virginia. The village of Boalsburg, Pennsylvania, also claims to be the first. A stone in a cemetery in Carbondale, Illinois, the wartime home of General Logan, carries the statement that the first Decoration Day ceremony took place there on Ap ril 29, 1866. Approximately twenty-five places have been named in connection with the origin of Memorial Day, many of them in the South where most of the war dead were buried. Official Birthplace Declared In 1966, Congress and President Lyndon Johnson declared Waterloo, New York, the birthplace of Memorial Day. A local ceremony held on May 5, 1866, was reported to have honored local soldiers and sailors who had fought in the Civil War. Businesses closed and residents flew flags at half-mast. Supporters of Waterloos claim say earlier observances in other places were either informal, not community-wide or one-time events. Confederate Memorial Day Many Southern states also have their own days for honoring the Confederate dead. Mississippi celebrates Confederate Memorial Day the last Monday of April, Alabama on the fourth Monday of April, and Georgia on April 26th. North and South Carolina observe it May 10th, Louisiana on June 3rd and Tennessee calls that date Confederate Decoration Day. Texas celebrates Confederate Heroes Day January 19th and Virginia calls the last Monday in May Confederate Memorial Day. Learn the Stories of Your Military Ancestors Memorial Day began as a tribute to Civil War dead, and it was not until after World War I that the day was expanded to honor those who have died in all American wars.  The origins of special services to honor those who die in war can be found in antiquity. The Athenian leader Pericles offered a tribute to the fallen heroes of the Peloponnesian War over 24 centuries ago that could be applied today to the 1.1 million Americans who have died in the nations wars: Not only are they commemorated by columns and inscriptions, but there dwells also an unwritten memorial of them, graven not on stone but in the hearts of men. What a fitting reminder to all of us to learn about and tell the stories of our military ancestors who died in service. How to Trace Your U.S. Military AncestorsAre You Descended from a Civil War Soldier?Discover Your American WWI AncestorsResearch Your Revolutionary War Patriot AncestorSymbols, Acronyms Abbreviations Found on Military Tombstones Portions of the above article courtesy of the U.S. Veterans Administration

Monday, May 11, 2020

Analysis Of Theodore Roethke s The Waking - 1335 Words

Though Theodore Roethke firmly lived his life in the modernist age, his works strongly echo the transcendentalist way of writing comparable to Waldo or Emerson; however, he personalized this form of writing through his own personal experiences. The foundations of his style of writing have strong origins in his childhood, where his family’s naturalistic lifestyle inspired him and where he developed a deep connection to the natural world through the greenhouses that his family managed. Due to this, one will almost always see the use of natural imagery in his writing to express more complex ideas. As one would expect, his poem â€Å"The Waking† is no exception. In this work, Roethke uses the interaction between the speaker and the natural world in order to embody the progression of cognitive awareness throughout the span of a single human life and to depict how one understands such knowledge through the senses, experience, and thought. Roethke opens the poem with the seemingly oxymoronic line â€Å"I wake to sleep, and take my waking slow† (1). At first, one may wonder, how does one wake-up to fall asleep? For these are naturally opposing ideas; however, here Roethke is not using literal definitions. Through the word â€Å"wake,† he is more likely referencing birth and the eventual enlightenment that one gains through life. Conversely, â€Å"sleep† represents death and, thus, the ceasing of intellectual gain. So, the first part of the line implies a dual meaning. Simply, the speaker is born only

Wednesday, May 6, 2020

Mountain Top Removal Free Essays

November 2010 Solution: Eight Letters, One word, Mountaintop Removal Mountaintop removal although only eighteen letters and a mere two words provides endless opportunities for hard working Americans. The world is now all about efficiency and convenience. Society works as a machine, and each machine needs fuel to work. We will write a custom essay sample on Mountain Top Removal or any similar topic only for you Order Now For Kentuckians, the fuel is Coal. The economy of Kentucky centers around coal. It not only gives hard working Americans a safe environment to work in but provides jobs, and stable economy for our nation. When compared to the rest of the world America has always had a strong economy. However America is currently in a state of recession. Politicians, cabinet members and economists are constantly trying to bring our great nation back into a state of equilibrium concerning monetary flow. Mountaintop removal is one way to achieve this. Areas which are abundant in coal are blessed with multiple lucrative opportunities which benefit not only the communities’ economy but the Nations, as well. Mine Safety is one thing that is extremely misunderstood. There is a lot of controversy, about mine safety regulations. But, the truth is that MTR is statistically the safest form of mining. Compare MTR to underground mining. Underground Mining: deep within the earth, hollow shafts, narrow tunnels, darkness all around, the fear that the mine may collapse at any time VS. MTR: Employees are above ground, have state of the art technology to help with safety protocol, and Mine collapsing isn’t a fear employees have to worry about. Jobs, something that loyal Americans are fighting for in the savage Job market. Mountain top removal offers long term jobs which also helps the economy. A fact, most people don’t know is that for every miner employed through MTR three new jobs are created. Thus, helping employment rates go up and keeping our economy running. Americans need jobs and through MTR we can make that happen. Mountain top removal: eighteen letters, three words, endless opportunities. Coal: four letters, one word, keeps the lights on. Although Opponents to MTR claim that it hurts the environment, creates a fair-weather economy, and is unsafe for its’ workers the truth is, MTR creates an almost identical landscape after reclamation, it continues to provides jobs even when the coal is gone and has been proven to be statistically safer than underground mining. Although the perspectives about MTR will continue to vary it is a lifestyle millions have adapted to already. Without MTR millions would be unemployed, the oven that makes our thanksgiving turkey would not work, a child wouldn’t have the electricity to read his or her first book. MTR is a permanent way to fix our problems. Kentucky is more than just a geographic state, it’s a state of mind and a state of heart and without MTR it would wither away into a perpetual end. Works Cited The Purdue OWL. Purdue U Writing Lab, 2010. Web. Date of access. Reece Erik , . Lost Mountain . New York : Riverhead, 2006. Print. Kitts, Gene. The Charleston Gazette. Charleston: Charleston Gazette, 2008. Print. Lemon, Eric. http://www. marshall. edu/cber/media/010420-DA-mountain. pdf. Charleston: Athenaeum, 2001. Print. How to cite Mountain Top Removal, Papers

Thursday, April 30, 2020

Lord Of The FliesPsychology Essay Research Paper free essay sample

Lord Of The Flies-Psychology Essay, Research Paper In sing the assorted facets of the island society in Golding # 8217 ; s Lord of the Flies as a symbolic theoretical account of society, a converse position must besides be considered. Golding # 8217 ; s island of isolated childs so becomes a universe, wherein the island represents the single homo and the assorted characters and symbols the elements of the human mind. As such, Golding # 8217 ; s universe of kids # 8217 ; s ethical motives and actions so becomes a study of the human status, both separately and jointly. Almost text edition in their portraiture, the primary characters of Jack, Ralph and Piggy are so best interpreted as Freud # 8217 ; s really constructs of Idaho, self-importance and superego, severally. As the Idaho of the island, Jack # 8217 ; s actions are the most blatantly driven by animalistically predatory satisfaction demands. In detecting the bang of the Hunt, his pleasance thrust is emphasized, purported by Freud to be the basic human demand to be gratifie d. We will write a custom essay sample on Lord Of The FliesPsychology Essay Research Paper or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page In much the same manner, Golding # 8217 ; s portraiture of a Hunt as a colza, with the male childs hungrily leaping atop the hog and brutalising it, alludes to Freud # 8217 ; s footing of the pleasance thrust in the libido, the term functioning a dual Lntendre in its psychodynamic and physically animal sense. Jack # 8217 ; s unwillingness to admit the conch as the beginning of centrality on the island and Ralph as the place of power is consistent with the portraiture of his peculiar ego. Freud besides linked the Idaho to what he called the destructive thrust, the aggressiveness of self-ruin. Jack # 8217 ; s antithetical deficiency of compassion for nature, for others, and finally for himself is exhaustively evidenced in his gratuitous hunting, his function in the barbarous slayings of Simon and Piggy, and eventually in his combustion of the full island, even at the cost of his ain life. In much the same manner, Piggy # 8217 ; s demeanour and really character links him to the superego, the scruples factor in Freud # 8217 ; s theoretical account of the mind. Golding Markss Piggy with the differentiation of being more intellectually mature than the others, branding him with a connexion to a higher authorization: the outside universe. It is because the superego is dependent on outside sup port that Piggy fares the worst out of the three major characters in the isolation of the island. Piggy is described as being more socially compatible with grownups, and carries himself with a sense of principle and aim that frequently serves as Ralph # 8217 ; s moral compass in crisis ; although Ralph ab initio uses the conch to name the others, it is Piggy who possesses the cognition to blow it as a signal despite his inability to make so. Similarly, Piggy # 8217 ; s spectacless are the lone artefact of outside engineering on the island, farther indicant of his correlativity to greater moral forces. In an about Gothic vena, these same spectacless are the lone beginning of fire on the island, non merely necessary for the boys # 8217 ; deliverance, but responsible for their ultimate devastation. Therefore does fire, and similarly Piggy # 8217 ; s spectacless, go a beginning of power. Piggy # 8217 ; s ideals are those most in struggle with Jack # 8217 ; s overpowering hungriness for power and repletion. It is in between these representations of pandemonium and order that Ral ph falls. Golding # 8217 ; s word picture of Ralph as leader is correspondent to Freud # 8217 ; s arrangement of the self-importance at the centre of the mind. Ralph performs as the island # 8217 ; s self-importance as he must countervail the natural desires of the Idaho with the environment utilizing the superego as a equilibrating tool. This definition is consistent with Ralph # 8217 ; s actions, sponsoring Jack # 8217 ; s wish to run with their corporate demand to be rescued, frequently turning to Piggy for advice. Initially, in the comparative harmoniousness of the island society # 8217 ; s early outgrowth, Ralph is able to equilibrate the opposing Idaho and superego influences in order to hammer a intent: deliverance. It is merely as the balance devolves that the destiny of the island # 8217 ; s dwellers is in darkness determined. Among Ralph, Piggy and Jack exists a changeless battle to asseverate their peculiar visions over the island. As the authorization of leading b y default falls to Ralph, the conch so becomes symbolic of the consciousness. Its ownership rotates between Ralph and Piggy in order to find logical classs of action for the male childs. Jack nevertheless, invariably eschews the authorization of the conch, consistent with Freud # 8217 ; s theoretical account with the Idaho by definition staying subconscious, but to the full able to exercise influence over decision-making. Conversely, the masks and face-paints that Jack # 8217 ; s group of huntsmans come to have on are really implicative of Freud # 8217 ; s image of the subconscious. The hidden and close nature of the boys # 8217 ; faces beneath their camouflages gives them a disguise intermixing them into the background of the island leaf, doing them unperceivable to the consciousness of the ego. Their actions go by and large unnoticed, but still have great impact on the island as they kill and destroy, finally overhunting the hogs they so urgently covet. The general assembly of the island, torn between the conch and the huntsmans besides becomes symbologically valid, going a menagerie of the other major human modules, some more of import than others. In Samneric comes a sense of trueness and fraternity in the deficiency of alone individuality between the twins and their fidelity to Ralph, even when captured and brutalized by Jack # 8217 ; s huntsmans. In Roger # 8217 ; s resolved devotedness to the bloody, bloodstained spirit of the Hunt lies a ruthless ferociousness that even Jack must trust on to accomplish his dark docket. Simon # 8217 ; s loss of emotional coherency and his disclosure give him a breakability coupled with a wisdom that make him an about neurotic defect in the coherence of island society ; he is ironically the strongest and the weakest nexus of the concatenation in his alone apprehension of their state of affairs. The older male childs so are the dominant modules of the mind, variably giving allegiance to each of the three major forces of the Idaho, self-importance and superego. As the biggest, strongest and smartest on the island, they are the beginning of achievement and accomplishment, both constructive and destructive. The emotions and human qualities manifested in the â€Å"littleuns† seem about repressed in comparing, congruent with their comparative ineffectiveness. Their incubuss and uneasiness impress a sense of fright, failing and anxiousness, while allayed, still spread to even the most mature of the island to some extent. Among the multitudes of male childs, Golding interpolates other images passingly implicative of Freudian psychosexual theory. Ralph # 8217 ; s first call to come together by blowing the conch implies a mention to the neonatal unwritten province, during which Freud postulated was the first struggle between desire and self-denial within a kid. Other mentions to jobs in acquiring the younger kids to adhere to toilet etiquette for wellness concerns allude to the anal phase, which psychodynamic theory hypothesized to be a period of increased consciousness of bowel motion during the toilet-training period in yearlings. Golding notes that the younger male childs call out for their female parents instead than their male parents, suggesting at the Oedipus composite. If the abandoned male childs are representative of the facets of the human person, so the alcoholic, rich premium of the island suggest the resources available to the person. The ab initio elaborate images of abundant fruit and t he tropical Alcyone idyll give a sense of splendor suggestive of the innate apparently illimitable charity of nature, non merely on the island, but in the human psyche. The initial # 8220 ; cicatrix # 8221 ; of the boys # 8217 ; reaching on the island presents the first mark of harm to paradise, climaxing in its ultimate incineration, about suggestive of Gotterdamerhng, the combustion of fabulous Valhalla. As such, other analyses of the island as a whole must take into history the island in a greater context. Piggy # 8217 ; s comparative rational adulthood and Ralph # 8217 ; s eventual deliverance at the custodies of British naval officers are so declarative of the function the apparently absent grownup universe plays on the island. The distinction of the grownup universe to the male childs and its presumed virtuosity elevate it to a much higher degree than the mundane universe of the island. Despite a passing mention to atomic war early on in the novel, the outside universe is really much assumed to be superior in operation by both the male childs and the reader, doing it an about godly figure in the graduated table of the island as a universe. The outside universe so becomes the ultimate universe, the cosmic cognition and wisdom of God. Ralph # 8217 ; s guilt at the British officer # 8217 ; s remark about the male childs # 8217 ; being British suggests a sort of bantering penite nce, both solemn and at the same clip satirising alleged British moral high quality. Ralph and Piggy # 8217 ; s want to be rescued so becomes a signifier of religion elevated to a intension of spiritualty. The signal fire so develops into a supplication for godly redemption, pass oning to the grownup universe a wish to be rescued spiritually. It is Jack and his huntsmans that care non at all for the care for the fire, despite the fact that it is their lone means off the island. They contrast Piggy as the signal fire # 8217 ; s greatest advocate, who as superego maintains a more externalized sense of what must be done. In set uping the island as a universe of the ego, one must so analyze the mode of Golding # 8217 ; s treatise on the human status as related to the secret plan of the narrative. The beginning of the male childs on the island gives birth to the person, the # 8220 ; long cicatrix smashed into the jungle # 8221 ; suggestive of some sort of built-in human failing, possibly a sort of Original Sin. Ralph # 8217 ; s name implies the first intimation of s elf-awareness as the male childs come to understand their state of affairs and the power construction of the island between Jack, Ralph and Piggy signifiers. The resulting formative stage of the island society so indicates growing and development, non free from errors and defects in the psychodynamic of the island, but come oning. The true downward bend in the island/person so comes as Ralph loses control of Jack # 8217 ; s huntsmans and Piggy # 8217 ; s subsequent decease. Golding # 8217 ; s grounds for prosecuting this class of action in the corporate sociology of the island is problematic. While it may be a mere exciting secret plan device, it is besides really possible within the context of the universe that Golding is in fact, portraying the island as a individual in decay. Previous events including the clang and assorted untended wildfires indicate the island has suffered significant injury. Golding # 8217 ; s pick to bring forth struggle between the Idaho and the self-importance may good be diagnostic of a greater crisis for the island/person, where it is reduced to an internalized conflict between its two cardinal psychological procedures. As such, Golding # 8217 ; s culminate dramas much like a morality narrative ; out of control, the Idaho destroys the single due to its suicidal nature, go forth ing merely the self-importance to reply to a higher authorization. As such, Golding # 8217 ; s judgement on world so takes on a really slantedly ambivalent tone ; in darkness pessimistic, merely passingly delivering in its sense of morality. In his decidedly Gothic stoping in this reading of the book, reminiscent of Poe, Golding remarks sourly even on apparently virtuous human modules such as righteousness and practicality. He portrays even the supporters with a humanly flawed skew ; Piggy is weak and whining, Ralph is ineffective. In their defects and Jack # 8217 ; s cursory efforts at virtuousness, Golding creates a balanced image of the individual, where no module is to the full good or to the full evil, but capable of being used to perpetrate Acts of the Apostless of either or both.

Saturday, March 21, 2020

Second Language Acquisition

Second Language Acquisition Many factors can influence the children’s success in learning the second language. Being brought up in the bilingual family, a person can develop speech skills in both languages simultaneously or in sequence. That is why, both languages can affect each other because of similarities or differences in their structures and semantics. Family and school environments are important to affect the process of learning two languages.Advertising We will write a custom research paper sample on Second Language Acquisition specifically for you for only $16.05 $11/page Learn More Thus, the degree of the second language learning and acquisition can be assessed with references to the number and character of errors made by the learner while using the second language for communicating with the other people. During the process of acquisition of two languages, a child can make developmental errors, transfer errors, and mix languages while communicating orally, and the char acter of these errors can be analyzed in order to make conclusions about the level of the second language acquisition. When a child is brought up in the family where parents use two languages to communicate with each other the child can make definite errors and mix languages while attempting to present his or her thought because these two languages used within the common environments can influence each other. Developmental errors are characteristic for a person when two languages are learnt simultaneously or when a child at the first stage of learning the second language (Paradis, Genesee, Crago, 2011). Developmental errors are the speech mistakes which can be made by any young person because the basics of the language are not learnt fully, and only the first efforts to use the second language correctly are made by a child. Thus, it is possible to state that developmental errors are rather natural in their character because they are not caused by the impact of the other language (P aradis, Genesee, Crago, 2011, p. 265). The examples of such errors are the wrong word order, grammatical mistakes, and the omission of morphemes. For instance, the child omits verbs and some prepositions and changes the word order because of lacking the necessary knowledge about definite grammatical rules. There can be errors in using the endings of words in relation to plurals or possessive cases (â€Å"then I said yes and then not my friends and then they ask me to be their friends again†) (Chloe, personal communication, 2013). From this perspective, a child can formulate the phrase or sentence inappropriately according to their structure because of omitting some important details such as the word order of subjects and predicates. Thus, the child can say ‘sever’ instead of ‘civil’ or ‘paying’ instead of ‘playing’ as a result of confusing words (Chloe, personal communication, 2013). These errors are caused by the similarit ies in the words’ pronunciation, but they are not affected by the particular features of the other language in which the learner can be more competent. That is why, these errors can be discussed as developmental ones.Advertising Looking for research paper on linguistics? Let's see if we can help you! Get your first paper with 15% OFF Learn More When errors in the learner’s speech are caused by the first language background these errors are discussed and analyzed as transfer errors. The role of transfer errors is important to examine and assess the level of the language acquisition from the point of the first language’s impact on the process of learning the second language (Baker, 2007, p. 212). The child can make transfer errors when he or she is confused in relation to the two languages’ differences and similarities. Thus, it is typical for children to accentuate words according to the accent patterns which are characteristic for the first language’s structure and rules. It is also possible to pronounce words while learning the second language according to the known patterns which are frequently used in the first language. It is important to note that transfer errors are more closely connected with language mixing than with developmental errors because they are caused by the usage of the other language (Baker, 2007, p. 215). Language mixing along with transfer errors is characteristic for learners who speak those two languages which are similar in their nature, used principles, and rules as well as in the pronunciation of many words (Hartsuikerl, Pickering, Veltkamp, 2004). The phenomenon of language mixing is observed when a child uses both languages simultaneously because of spending much time within the environments where people speak two different languages (Heredial Altarriba, 2001). Living in the bilingual family, a child can mix languages in order to adapt to the situation and provide the nec essary word or phrase quickly and without concentrating on the language used (Hartsuikerl, Pickering, Veltkamp, 2004). There are a lot of concepts and notions which are operated in the family in one language in spite of the concrete situation of communication and language which can be used in relation to these definite circumstances (Greene, Pena, Bedore, 2013). Thus, the child can be inclined to mix languages while speaking about his or her family. For instance, grandmother and grandfather can be referred to as ‘Nana’ and ‘Tata’ because these concepts are frequently used in the family in order to speak about relatives as well as father can be called not ‘daddy’, but ‘papito’ (Chloe, personal communication, 2013). The first and second languages are mixed because these words are used while speaking in English. Language mixing is typical for young children because they do not analyze the fact of speaking two different languages, bu t children use the word which is more common for them, for instance, ‘Nana’ and ‘Tata’ instead of grandmother and grandfather.Advertising We will write a custom research paper sample on Second Language Acquisition specifically for you for only $16.05 $11/page Learn More The low percentage of developmental errors and language mixing indicates the good level of the second language acquisition. Thus, the frequent usage of such words as ‘Nana’, ‘Tata’, and ‘papito’ cannot be discussed as the influential factor to speak about the low level of the second language acquisition. However, the problems with structuring sentences and providing grammatical forms of words which can be analyzed as developmental errors are important to make conclusions about the level of learning the second language with references to learning and using its basic principles (Baker, 2007). Therefore, the degree of the second l anguage learning can be assessed by teachers with the help of examining the learner’s developmental and transfer errors and language mixing. Developmental errors are characteristic for the first stages of learning the second language when the key rules are learnt and skills are improved. The concepts of transfer errors and language mixing support the idea about the impact of the first language on the process of learning the second one. From this perspective, the situation of children’s language mixing can be discussed as more typical for bilingual families where both languages are learnt simultaneously. References Baker, C. (2007). A parents’ and teachers’ guide to bilingualism. Clevedon: Multilingual Matters. Greene, K., Pena, E., Bedore, L. (2013). Lexical choice and language selection in bilingual preschoolers. Child Language Teaching and Therapy February, 29(1), 27-39. Hartsuikerl, R., Pickering, M., Veltkamp, E. (2004). Is Syntax Separate or Shared Between Languages? Cross-Linguistic Syntactic Priming in Spanish-English Bilinguals. Psychological Science, 15(6), 409-414.Advertising Looking for research paper on linguistics? Let's see if we can help you! Get your first paper with 15% OFF Learn More Heredial, R., Altarriba, J. (2001). Bilingual Language Mixing: Why Do Bilinguals Code-Switch? Current Directions in Psychological Science, 10(5), 164-168. Paradis, J., Genesee, F., Crago, M. (2011). Dual language development and disorders. Baltimore, M. D.: Brookes.

Thursday, March 5, 2020

Learn How To Paraphrase Properly With The Best Online Guide

Learn How To Paraphrase Properly With The Best Online Guide Learning to Paraphrase: A Step-By-Step Guide Paraphrasing is often not taken seriously both by students and teachers, while students think it is the easiest task ever, and teachers, in turn, assume that every student knows well how to do it. There is a good reason for the professors to think so. In our daily speech, each of us paraphrases several times a day, for example, various morning or talk show conversations or phrases, friends, parents, blogs, etc. We all live and communicate. Every day we render something said earlier by one person to another person or party, and we don’t do that word for word. So, paraphrasing is a natural way for all humans to convey information. Thus, if we do it so often, it’s possible to assume everyone knows well how to do it well. However, it’s crucial for students to know how to do it in order to avoid plagiarism. Besides, mastering this skill will allow you citing someone’s ideas without a need of a word for word quotation. When you are able to paraphrase pro perly, you have a chance to make your writing diverse and show how you mastered the material. What Is Paraphrasing? Paraphrasing means to keep the meaning of the original text without copying its exact wording. Massachusetts Institute of Technology defines paraphrasing as taking the words of another source and using your own vocabulary to restate them. A paraphrase is actually swapping the keywords not to parrot the author and render his main idea at the same time. Yes, it may sound really simple, however, there are so many students having troubles with it. The problem is that when paraphrasing, they misinterpret the main idea of the original text. Linguistic scholars define full paraphrase and quasi-paraphrase. According to Bhagat Hovoy, it can cause very subtle but still very essential meaning, implication, and point of view differences. Bhagat Hovoy define paraphrasing as phrases or sentences rendering almost the same meaning through using different words. The Difference Between Paraphrasing and Plagiarism The main difference between paraphrasing and plagiarizing is very simple, correct paraphrasing usually has a source attached or cited. When citing someone else’s source you show that you do not try to produce someone’s work for your own. Ideas are really valuable in academia, so if you try to pass off someone’s idea as your own, it is perceived as stealing. And there is a good reason for that, while some academics spend much time on their studies to come up with those ideas, and stealing them is a serious offense. They might be just phrases or words for you, but those ideas are the result of someone’s hard work. When paraphrasing, you don’t only change the main words but also the sentence structure, and at the same time, you give some new life to the text. According to some experts, if a paraphrase has seven or more words from the original source and it is not acknowledged properly, it is considered to be plagiarism. It is necessary to save the meaning and intent of the original idea as much as possible, but the words and vocabulary, in general, have to be different. It is a sort of following a recipe and at the same time, substituting each ingredient by something else and getting the same dish at the end. And don’t forget to state the original author in the reference. The Difference Between Paraphrasing and Summarizing When summarizing, you can gather all the main ideas of another thinker or author in their core concepts. There is a very small difference between a summarized paragraph and a paraphrased one. A paraphrased paragraph, as a rule, is aimed to give the main idea of what it is referring to. A summarized paragraph is intended to show the main points and ideas of the initial source. Both of them must have citation and references to the original source. It is very possible to make a properly paraphrased summaries and even plagiarized summaries. A summary that is paraphrased properly should restate a written summary via new vocabulary and structure. It also requires correct in-text citation. A plagiarized summary will restate the same original summary’s ideas using many the same keywords. And it is not referred to the original author. How to Paraphrase It requires some skills and practice to paraphrase a point, argument, or idea of another person. The following tips will help you master this skill the soonest. The order of the words and sentence has to be adjusted. Before thinking of new words for your sentence, you should change the whole structure of the sentence. A new sentence should start at a different place than the original one. This way, you will have to make wording changes. For example: The meeting was rescheduled while the deputy had to go to the head office. – The deputy head to go to the head office, so the meeting was rescheduled. So, you just restructure your sentence and can start substituting the words to paraphrase your own sentence. Such restructuring impacts the tone, too, it brings freshness to the original idea. Sometimes paraphrasing allows making the ideas of an academic more understandable and readable, especially if you make the sentence structure easier. When restructuring, you are free to change the length of the sentence. You can make too long sentences shorter, and vice versa, combine few short sentences into a longer one. The writing manner of some academics requires the readers to read the sentence over again in order to understand it, so you can restructure it and make it easier and accessible to your reader. Substitute new words. This step is one of the most crucial to write a proper paraphrase. When using new vocabulary, you show your ability to understand everything that was said by the author and at the same time, choose the synonyms conveying the same meaning. Too complicated and esoteric words can be replaced with easier ones. And vice versa, too generic words can be replaced with those that express the main idea better. If you want to use some set phrases, you can still do it. If you want to refer later to the original turn of the author’s phrase, you can also keep it. If necessary, add the definition of terms. One of the best paraphrasing benefits is the opportunity to improve the original work. If the author didn’t provide any illumination, you can do it. Review the paraphrased sentence and check if you didn’t change the meaning drastically. It is crucial for paraphrasing. Sometimes, it is necessary to simplify the tone of the original expert to show your understanding of the material and ensure that you didn’t just alter the original meaning. Some synonyms may alter the original meaning of the text, so make sure to choose the proper ones. Paraphrase Example Original: â€Å"The world has a great writer in Erich Maria Remarque. He is a craftsman of unquestionably first rank, a man who can bend language to his will. Whether he writes of men or of inanimate nature, his touch is sensitive, firm, and sure.† (The New York Times, 2007). Paraphrased: Erich Maria Remarque is a great writer of the world. He is a first rank mater who is able to make the language obey his will. His touch is always sensitive, confident, and sure, no matter what he writes about. (The New York Times, 2007). How to Cite a Paraphrase MLA Format The MLA format requires to state the name of the author and the number of the page within parenthetical. For example: (Dickens, 25). However, if you mention the name of the author in the paraphrase, you have to use only the page number at the end. For example: According to Dickens, †¦(25). APA Format This format requires you to use the name of the author and the date within a parenthetical. For example: (Dickens, 1843). In case the author is cited within the paraphrase, just state the data at the end. For example: According to Dickens, †¦ (1843). Chicago Format This format requires you to use the footnotes for referring to a citation within the text. It’s necessary to state the full name of the author, the work title, the date of publishing, the year published, and the page numbers. For example: Charles Dickens, A Christmas Carol, (London, 1843), 25. If you refer to the work for the second or more times, then use the abbreviation of the citation For example: Dickens, Christmas, 25. Paraphrasing Tools Fortunately, modern technologies develop fast and make students’ life even easier. Such tools help not only finds variants for their writing but also check it for various spelling and punctuation mistakes. You can also use various plagiarism checking programs to make sure your work is unique. Conclusion Anyone possesses the ability to paraphrase. It will be very helpful for you to master these skills to improve your writing abilities and make them more diverse. With the help of paraphrasing, you don’t seem to be dependent on the expertise research. The more you practice, the easier it will be for you to paraphrase.

Monday, February 17, 2020

FDI (Foreign Direct Investments) determinants in Greece and the impact Dissertation

FDI (Foreign Direct Investments) determinants in Greece and the impact of thr single European currency on the attraction of FDI - Dissertation Example The typical factors that bring FDIs in Greece mostly influence the capital productivity, decisions of foreign investors, and the labour costs on the sectoral level. In the conclusion, the paper provides significant policy implications. Table of Contents Table of Contents 2 1. Introduction 3 2. Literature Review 6 3. Locational Determinants of FDI INWARDS in Greece 10 4. Description of variables and hypotheses 15 6. CONCLUSIONS AND POLICY IMPLICATIONS 26 References 29 1. Introduction FDI is considered as the most important economic force in the world. The proportion of FDI in services sector is rapidly attaining great importance (United Nations Conference on Trade and Development, 2004). Special attributes making the treatment of FDI unique in the service sector include the coherence between the products’ production and consumption, the urgent requirement for local adaptation and the significant impact of quality (Boddewyn et al., 1986; Dunning, 1989). The services play a cruci al role in the entire process of production. For instance, the presence of the framework (Ramamurti and Doh, 2004) or financial services are regarded as the economy’s backbone. However, the small share of the services in the world’s exports, which is only 20 percent (IMF, 2003) highlights their non-tradable nature. Due to this specific attribute and in order to remove the trading restrictions, several businesses decide to support the domestic market with the FDIs. In services, the FDI inward stock of the world has increased from USD 950 billion to more than USD 4 trillion whilst the previous decade. At present, the FDI inward stocks in services account to over 60 percent of the total inward FDI stocks around the globe. Thus, in order to support their group internationally, numerous Multi-National Enterprises (MNEs) opt to invest in trading, marketing and financial intermediation associates. This shift of FDI flows to services is explained through the case of Greece in this study since Greece has been conventionally receiving FDI from the early 1950s. Most of the FDI flows were directed towards the sectors of basic metals, chemicals and transportation during the decade of 1963 to 1973 which extensively supported the revival and enhancement of the industrial base of the country. However, after the induction of Greece to European Union (EU), a smooth change occurred in the structure of FDI in the early 1980s. On the other hand, during the 1980s and 1990s, the FDI flows were targeted towards the industries of food, textiles, beverages and consumer electronics. The governments of Greece during that period took significant measures to lead the Greece towards rapid and sustainable development through enhancing the competitive advantages of its economy as it converged with the core countries of EU. These measures were further reinforced through targeted EU policies that specifically included Community Structural Funds and Cohesion Funds. The major part o f this support was inclined towards the development of infrastructure where as just a small portion of it was dedicated to education, training and capital (Paliginis, 2001). Presently, the objective of the policies at Greece is to encourage and attract FDI. Most of the industries in Greece are open to international investors, with the telecommunications sector being de-regularized as well as the energy industry being

Monday, February 3, 2020

National Express rejects takeover bid from First Group (Financial Research Proposal

National Express rejects takeover bid from First Group (Financial Times, 29 June 2009) - Research Proposal Example 1.2 billion pounds to banks (Gill, 2009, p 1). The United Kingdom government has also complicated National Express financial woes by the government refusal to renegotiate the conditions for its East Coast rail franchise with the transport business. The hard-line position adopted by the government is attributed to East Coast rail franchise being the most lucrative in the United Kingdom serving the United Kingdom commercial hubs such as Edinburg and London. Besides, citing the government role in its financial crisis, National Express board also cited its quest to solve the ?1.2 billion debt as its first priority before reconsidering the bailout from FirstGroup limited. In, addition, National Express board viewed FirstGroup as their rival in the transport business and thus postulated a sellout of the company to FirstGroup as surrender to a business enemy. National Express boards were thus eager to retain the legacy of their company’s in the transport industry (Miller, 2011, p 85) . Despite, the rejection of FirstGroup offer, acquisition and acquisition provide the best bailout opportunity and option to rescue National Express from the current financial hardships. This research thus draws on the case sturdy of National Express and FirstGroup to rationalize on the best solution to solve a corporate organization financial solution. This involves an analogy acquisition and acquisition as a financial solution with other financial crisis solution mechanisms recommended in fiance and accounting. The research establishes higher financial crisis solution rationality from acquisition and acquisition formulated financial solution compared to other possible and readily available financial and accounting options. Literature Review An acquisition mimics government bailout to corporations during financial crisis. The similarity between acquisitions and acquisition is evident in the supply of a large amount of money to the corporation under financial crisis, which is subseq uently used to pay its bankruptcy threatening debts. These facts are manifest in the proposed acquisition between National Express and FirstGroup, whereby Nation Express was offered a large sum of money by FirstGroup to pay its 1.2 billion debts. The ?1.2 billion proposed buyout of National Express is comparative to the government’s financial bailout to financial corporation during the 2007-2008 global financial crises (Milmo, 2009, p 1). In United States, the government acquisition styled bailout totaled $13.9 trillion leading the government bailout to be considered as more of an acquisition buyout of the financial stricken institutions than a rescue bailout package (Birdsall & Fukuyama, 2011, p 31). Acquisitions and acquisition of financial stricken corporations is also licked to the nationalization of finically poor performing or financially endangered businesses by the government (Finkelstein & Cooper, 2010, p 116). The same financial crisis incident illustrates the role of nationalization which mimics acquisition and acquisitions in the rescue of financial institutions from bankruptcy during economic downturns. A typical example of this financial rescue strategy is illustrated by the nationalization of the Northern Rock Bank in the United Kingdom at the verge of its bankruptcy during the financial crises. The Northern Rock Bank case also illustrates the irrationality of the hard-line position by a corporation board or the corporate organization stakeholders,

Sunday, January 26, 2020

Exosome as Nanoscale Vesicles | Pancreatic Cancer Research

Exosome as Nanoscale Vesicles | Pancreatic Cancer Research Abstract Exosome are nanoscale vesicles that are released from cancer cells, playing an important role in the microenvironment of cancerous tumour cells.6,8 The exosomal vesicles (EV) contribute to the progression and growth of the tumour, and can be targeted using gold nanoparticles (GNP).1,6,7 The exosomes are isolated from the blood plasma, and with their stability in bodily fluids, they can be targeted and inhibited using GNP.   The GNP will inhibit the cancer cell, and will stop tumour growth and production.   Using proteomic and quantitative methods, the exosome EphA2, showed the highest detection of specificity and sensitivity in pancreatic cancer patients.1,2,4,8 Further tests confirmed that EphA2-EV has potential in early detection for pancreatic cancer, due to the levels specificity and sensitivity being higher in comparison to pancreatitis patients and the control patients.1 Keywords: Biomarkers, Exosome, Pancreatic cancer, Nanoparticle, Proteomics, Vesicles, Plasma, Antibody Introduction Pancreatic cancer, is vastly terminal, with a survival rate of less than 5%.   Pancreatic ductal adenocarcinoma (PDAC), is the most common form of exocrine pancreatic cancer, accounting for around 95% of pancreatic cancer cases.10 PDAC is a silent cancer, and with the lack of testing, the need for novel biomarkers to aid in early detection is imperative.   With no valid early detection methods, and no symptoms of early stage PDAC, the cancer will progress rapidly throughout the body before it is detected.   There is need to find a biomarker, aiding in the early detection PDAC, so that a treatment can be provided to stop the cancer from progressing.   The current tumour biomarker, CA19-9, is not reliable in early detection due to falsely elevated results of diseases other than PDAC.10 Recent studies suggest that exosomes, a nanovesicle, has a high potential as the future biomarker of PDAC, due to the stability and detection sensitivity in human blood plasma.1,2,4,8 Malicious exosomes, are veiled by cancer cells, screening the importance in tumour maturation and progression.7 Studies show how to optimize a method, to isolate exosomes from the blood plasma, to further assist in biomarker discovery.   In regards to analysing exosomes as a potential biomarker, exosomes need to purified and isolated with differential centrifugation paired with ultracentrifugation (UC).   Another technique used, is affinity purification of the exosomal membrane antigens using density gradient (DG) centrifugation, separating the vesicles based on their density.8 A practise needs to be conducted, to purify exosomes, from only a small volume of blood plasma. With studies being conducted on the stability in fluids of circulating exosomes, it can be confirmed that these nanovesicles have the ability of targeting to uptake to hinder or delay tumour development.   With the size of the exosomes ranging from 40 100 nm, they are distinguished for tumour microenvironment.   Exosomes, a potential biomarker, for the early detection of PDAC, are also being studied as potential nanocarriers to target cancer cells and delaying tumour growth.1,7,8 The most common nanocarrier being studied is the gold nanoparticle (GNP), due to its imaging, diagnostics, and therapy abilities.   The GNP can be easily synthesized via the citrate reduction, which is why is has potential in medical theranostics.7 Extracellular vesicles (EV), are secreted into extracellular space, they are involved in tumour initiation, progression as well as metastasis.   EVs can be used as non-invasive biomarkers, but the current studied methods are time consuming in regards to EV isolation.1,7,8 The EV membrane markers which are part of the tetraspanin family, are CD9, CD63, and CD81, respectively, and an assay demonstrates similar features.6 A nanoparticle EV assay, will be captured by an EV-specific antibody with the dual binding of EV, using 2 nanoparticle probes.   The 2 nanoparticle probes, will produce a plasmon, promoting an increase in sensitivity and specificity for the discovery of an exosomal biomarker.   Ephrin type A receptor 2 (EphA2), has recently been identified as a biomarker, of the tumour derived pancreatic cell line, and enriched on EV.1   EphA2, shows overexpression, increases in vitro invasiveness and anoikis resistance in pancreatic cancer cell lines.1 A recent study has been conducted with healthy control patients, pancreatitis patients as well as pancreatic cancer patients, with the use of nanoplasmon-enhanced scattering (nPES) assay a fast, sensitive, and specific method in biomarker detection. Convention Tumour Markers in Pancreatic Cancer Carcinoembryonic Antigen CEA CEA, is a glycoprotein, that is measured in a common blood test used for testing patients with cancer, including pancreatic cancer.   This will measure the amount of the CEA protein that is in the blood of a patient who may have cancer, and the CEA levels can be used to determine whether treatment is working or if the cancer is spreading.   A CEA level of 5 ng/mL, is considered a normal level of this protein, but there are several conditions that can alter the levels of the CEA in your blood, which is why this is not a valid biomarker in the detection of pancreatic cancer.5 CEA testing can be useful in regards to recurrent colon cancer as well seeing if treatment is successful.   Levels of CEA can be elevated due to smoking, as well as in other diseases such as Crohns disease.   Due to the unreliability of CEA levels in cancer, this blood test confirms that CEA is not a consistent biomarker for the early detection of pancreatic cancer. CEA is expected to be paired with other biomarkers, for early detection reasons.   When paired with CA19-9, there is an increase in detection for sensitivity and specificity, showing an improvement in diseases including pancreatitis as well as pancreatic pseudocyst.   Despite the improved results for pancreatic diseases, CEA is still not valid for the detection of pancreatic cancer, even when it is paired with another marker such as CA19-9.5 Carbohydrate Antigen CA19-9 Carbohydrate antigen (CA19-9) was discovered in 1981, and is considered a sialyl lewis a (sLea).9 CA19-9 is found on the surface cancer cell, expressed as a glycolipid and an O linked glycoprotein, and is related to the Lewis blood group antigens.3   Patients with Le (alpha beta +) or Le (alpha + beta -) blood group, express levels of CA19-9 in their blood, whereas approximately 5 10% of patients with Le (alpha beta -) blood group do not express CA19-9, limiting the use as a valid biomarker.9 Due to the low, and uncertain sensitivity of CA19-9, it is a poor interpreter of PDAC, therefore it is not a valued biomarker. CA19-9 is unable to differentiate between benign, precursor lesions and malignant conditions in PDAC patients, and it gives elevated results in many other gastrointestinal cancers.3   This blood test can show elevated CA19-9 levels in patients with other non-cancer diseases including pancreatitis and cirrhosis.3,9 The CA19-9 blood test can be beneficial in regards to knowing if a pancreatic tumour is secreting it, and to judge the efficiency of treatment, and look for pancreatic cancer recurrence.   A healthy patient will have a CA19-9 level of 0 37 U/mL, therefore with increasing levels of CA19-9, this could indicate tumour growth.3 For more accurate results, a PDAC marker needs to be discovered and paired with CA19-9, to increase the sensitivity and specificity in early detection.   With CA19-9 as the only marker, studies show it was only elevated in 50 75% of patients having PDAC, confirming that is not consistent as a biomarker and should not be used in diagnostic testing.3,9 Expressing elevated levels in other diseases such as benign jaundice, pancreatitis, and ovarian cancer, confirms the lack of consistency using the CA19-9 marker and that it cannot be used as an accurate indication of early pancreatic cancer detection.3 Emerging Biomarkers With the absence of reliability using the current PDAC biomarker, C19-9, it is a necessity to discover a biomarker with improved sensitivity as well specificity for the early detection of PDAC.   Recent studies suggest, that exosomes can be detected in body fluid such as blood, and they have potential as disease biomarkers.   Exosomes, found in blood plasma, need to be collected from healthy patients to obtain individual and pooled samples.   The collected blood plasma, will need to be separated, by centrifugation, to isolate the exosomes for further proteomic and quantitative studies.8 Isolation Methods Isolation of exosomes using the UC method, involves normal human plasma, and diluting it with PBS.   The sample will be differentially centrifuged, to eradicate cell debris, which is followed by UC.   The subsequent pellet, is washed in PBS, and filtered, and the filtrate was ultracentrifuged.   The resulting exosomal pellet, used for the study, will be resuspended in PBS.8 Using the EI isolation method, the plasma, is diluted in PBS and centrifuged.   The supernant is filtered, and the filtrate will be incubated using a blocking agent.   A microcolumn was placed in magnetic separators, where the column was rinsed with rinsing solution.   Beads were bound to the exosome, and were applied to the magnetic column.   The column will be washed with rinsing solution, and the immune captured exosomes were recovered by removing them from the column and placing them in a collection tube.   The exosome bound microbeads are washed to elute the exosomes, and centrifuged to obtain the exosomal pellet.   The exosomal pellet will be resuspended in PBS.8 Lastly, isolation using DG method, involved the exosomal pellet that was obtained from UC as well as normal blood plasma that was layered on iodixanol solution and centrifuged.   To the top of the tube, there were 12 fractions, with increasing densities.   The fractions are diluted with PBS and centrifuged, the resulting pellet was washed with PBS, centrifuged and resuspended in PBS.8 Western Blot and Microscopic Analyses The western blot method, shows the enrichment of the exosomal marker proteins.   Gel electrophoresis is used to separate and identify the different proteins.   The thickness of the band, indicates the amount of the protein that is present.   There is a labelled antibody, that is bound to the protein of interest.   AFM is used, to get a 3D image of the exosomal vesicle. Recent studies confirma that the exosomal markers CD9 and CD63 are enriched in exosomes purified using UC and EI methods.8 The study indicates that the UC method, had four exosomal markers whereas the EI method had only two exosomal markers, CD9 and CD63.   Transmission electron microscopy (TEM) and atomic force microscopy (AFM), were used on the isolated exomes, from the three exosomal isolation techniques.   In the DG sample, the TEM reported homogeneous vesicle, with diameter ranging from 40 100 nm, confirming the characteristics of exosomes.   The AFM produced a 3D image of the exosome, and after further analysis it was revealed that the exosomes had round membranous vesicle characteristics. LC-MS/MS Liquid chromatography mass spectrometry (LC-MS/MS), is a quantitative method used for the identification of proteins at the peptide level.   The first quadrupole is for the selection of the precursor and the second quadrupole is highly specific for detection.   In comparison to gas chromatography mass spectrometry (GC-MS), LC-MS/MS is not limited to volatile substances, it is better for the detection of molecules.   LC-MS/MS can produce many quantitative results, and has a high specificity and sensitivity. The study was carried out, using an LTQ Orbitrap Velos with a nanoelectrospray interface coupled to an Ultimate 3000 RSLC nanosystem and the LTQ Orbitrap Velos mass spectrometer operates using a nano -ESI spray.   The LC-MS/MS spectra are searched against the human protein database using MASCOT.   Equal amounts of protein from the three exosomal samples were separated, reduced, alkylated and digested with trypsin.   The DG sample had the highest number of protein identifications, followed by the UC isolation method.   Therefore, the western blotting, microscopy and MS results confirm that the DG isolation method is the most effective, in regards to isolating exosomes from blood plasma.8 Targeting with Gold Nanoparticles Malicious Exosomes The exosomes are formed from endosomal pathways, after they are fused from multivesicular bodies (MVBs) with plasma membrane.   The formation of malicious exosomes, also starts in the endosomal pathway.   The early exosome is formed from the migration from the cell periphery to the nucleus, by the formation of intraluminal vesicles (ILV).   The process interceded by exosomal complexes required for transport (ESCRT) and other proteins.   Late exosomes/ MVB, migrate to the periphery and fuse with the membrane, releasing the ILV, which are called exosomes.   The proteins, Rab GTPases, mediate the endosome migration.7 The malicious exosomes, are released from cancer cells found in the tumour microenvironment.   Exosomes play a role in variation and shaping of that tumour microenvironment.1,2,4,6,8 Malicious exosomes have potential as biomarkers, due to their stability in biological fluids including blood plasma.   There have been increased levels of circulating exosomes seen in several cancers including pancreatic cancer.1,6,7,8 Nanovesicles can be used to carry therapeutics, and have potential to limit cancer progression.1,7 The method consists of inhibiting the malicious exosomes biogenesis. Gold Nanoparticles The GNPs can be easily synthesised, as well they consist of a variety of shapes and sizes.   These nanoparticles exhibit intense light absorption and scattering, and they are deemed to be highly stable.1,7   They have potential in targeting, therapeutics as well as diagnostic capabilities. Regarding rapid tumour growth, a compressed lymphatic vessel will collapse causing lymph drainage, which will then allow for the nanosized molecule to be taken at the tumour site.7 This process will allow for passive targeting with nanosized molecules.   The cellular interest will be dependent upon the size and shape of the GNP.1,7 The tumour cells will overexpress their cell number receptors, which can be used for potential biomarkers.1,2,4,6,7,8 These cell surface receptors, will aid in the direction of the GNP to the tumour cells. Gold Nanoparticle Targeting The GNP will target malicious exosomes, by undertaking the malicious exosomes biogenesis with GNP specific targeting moieties as well as silencing moieties.7   Using antibodies to aim at the exosome for capture and selective retention.   Lateral flow immunoassay, will aid in exosome detection with CD9 and CD81 as antibodies, and CD63 with GNP.1,7 Therefore, GNP are being studied as a potential candidate for cancer therapy as well as for malicious exosome targeting.   The use of nanotheranostics to help quantify and inhibit the malicious exosomes. Sample Collection and Processing This recent study, developed a method for the purification of exosomes in blood plasma, as well as finding the EV concentrations in the plasma samples.   A three-probe EV capture was used, with a capture antibody that recognizes an EV membrane protein (anti-CD81), with antibody conjugated AuS and AuR to serve as two EV probes.   This EV capture was designed to form a plasmon, with the different GNP binding on an EV to improve sensitivity and specificity of EV detection.1   The study examined 59 pancreatic cancer patients, 48 pancreatitis patients, and 48 control patients, to see if early pancreatic cancer stage could be distinguished from pancreatitis patients and the control patients.1 Method The EV isolation consisted of cells grown in culture media, and washed with PBS.   The culture supernatants were collected and centrifuged to pellet cells, and centrifuged again to remove cell debris.   Concentrated with centrifugal filtering units, and centrifuged, the precipitates were collected and resuspended in PBS and centrifuged.   The resulting precipitates were collected and dissolved in PBS.   The ELISA assay, consisted of ninety-six well plates, which were incubated with antibody CD81.   The ELISA assay was analysed for absorbance, and the standard curve plotted the light absorbance versus the log10 EV standard concentration in pg/uL.1 The peptides were separated using Ultimate 3000 nano-LC, with an enrichment column as well as an analytical column.   The peptide fractions were analysed with Velos Dual-Pressure Linear Ion Trap mass spectrometer, and one MS scan, was followed by eight MS/MS scans. The nPES platform was constructed by filling sample wells with plasma sample or cell culture EV samples, followed by incubation and being washed three times with PBST and three times with PBS.   The sample wells were then filled with AuS and AuR PBST solution, and were incubated and washed three times each with PBST and PBS, respectively.   The sample wells were fitted with a cover slip and dark-field microscopy (DFM) was used for imaging.   The DFM images, that had image areas with brightness equal to 225 were selected, and the ratio of the image area to the whole image gave area ratios that were indicative to the nPES EV signal.1 A standard concentration curve was generated with a linear regression of nPES area ratio with log10 concentrations.1 SEM images analysed the images of GNP binding to EV, from EVs that were purified from human plasma.   The purified EVs were hybridized with anti-CD63-AuS and anti-CD9-AuR.   The SEM fields were analysed to calculate the total EVs, as well as the number of GNP-bound EVs per um2 of each assay. Proteomics and the Early Detection of PC An nPES was previously designed, for EV detection using GNP, that can scatter light at different wavelengths indicative to their shape and size.   Using both gold nanospheres (AuS) as well as gold nanorods (AuR), a plasmon is formed, increasing the scattering intensity.   With the plasmon, antibodies against CD9, CD81, and CD63 can capture and detect EV in a sample.1,7   AuS and AuR are detectable using dark field microscopy (DFM), and will form the complexes AuS-EV-AuR, AuS-EV and AuR-EV.   These complexes can be analysed using scanning electronic microscopy (SEM), examining the binding and distribution.   Following the pure preparation of EV samples, EV plasma was added to give the EV plasma standard.   The anti CD81 was incubated with the standard and two antibodies conjugated GNPs, AuS-Anti-CD63 and AuR-Anti-CD9, which exhibited ratios >0.35%.   A comparison was done with nPES and enzyme linked immunosorbent assay (ELISA), of the sensitivity and linearity of thei r EV values.   The nPES assays showed to be highly sensitive, requiring less plasma as well has exhibiting more advantages over ELISA in regards to measuring EV concentrations.1 Since CA19-9 is the only accepted pancreatic cancer marker that is not valid, pancreatic cancer derived EV marker is a more feasible biomarker due to the multiple factors that the pancreatic cancer cells express.   The nPES assay will quantitate tumour derived EV from blood samples, and one of the two EV specific GNP were replaced with one specific for the membrane protein.   LC-MS/MS proteomics, bioinformatics is used to identify trans-membrane proteins on EV PC (PANC-1 and MIAPaCa-2) and PDAC (BxPC-3).1 There were 128 membrane proteins identified, and 26 were expressed on EV.   The EphA2 showed the highest expression and is associated with cancer progression, metastasis, and prognosis.   The EphA2, was also not expressed by EV in HPNE. EphA2 was chosen as the potential marker, and CD81 and CD9 were chosen for EV capture.   The nPES was modified, using one capture antibody (anti-CD81) and two antibody-conjugated GNP probes (anti-EphA2-AuS and anti-CD9-AuR).1 The plasma EphA2-EV levels were higher in pancreatic cancer patients, in comparison to pancreatitis patients and the normal control (NC).   With the strong association between the circulating EphA2-EV and early stage pancreatic cancer, there is potential for EphA2-EV to be used as an early detection marker.1   The CA19-9 levels were increased in the pancreatic cancer patients in comparison to the pancreatitis patients and the NC, but the levels were not increased in the early stages of PC.   The receiver operating characteristic (ROC) curves, showed that the plasma EphA2-EV levels are promising in the classification of pancreatic cancer stages. The current EV analysis methods are tedious and lengthy for the isolation procedures, as will having volume requirements.   The nPES platform that has been studied, assimilates EV capture and detection with the use of the plasmon coupling effect, to have an increase in both detection sensitivity and specificity in small volume samples and fast sensitive biomarker quantification.   This EV nPES platform, can be generalizable for any disease state that has a specific EV marker.1  Ã‚   The nPES EphA2-EV blood assay shows substantial value regarding pancreatic cancer screening tests, due to being a rapid, accurate and non-invasive blood test for the early diagnosis of pancreatic cancer. Conclusions This review article explains the need to find a valid biomarker in the early detection of pancreatic cancer, as well as discussing how exosomes have potential to be that marker in the early detection process.1,2,4,6,7,8   The existing biomarkers for pancreatic cancer, are not valid markers in the early detection due to the lack of sensitivity and specificity that they exhibit when differentiating between benign and malignant stages.   The use of exosomes for the early detection of pancreatic cancer, shows potential as a biomarker, with the use of nPES platform.1 The platform allows for EV capture using plasmon coupling, which increases in detection sensitivity and specificity, which allows for the discovery of an ultrasensitive biomarker.   The nPES EphA2-EV assay could differentiate between pancreatic cancer patients (stage I and II) and pancreatitis and NC patients.1 The role of EphA2-EV, could help to improve early detection rates as well as improving patient outcome, and th is blood test is inexpensive, accurate and non-invasive.   This review involved proteomic and quantitative methods, to find a novel biomarker for the early detection of pancreatic cancer, and non-invasive nPES EphA2-EV analysis can aid in improving early pancreatic cancer detection and treatment. References Liang, K.; Liu, F.; Fan, J.; Sun, D.; Liu, C.; Lyon, C. J.; Bernard, D. W.; Li, Y.; Yokoi, K.; Katz, M. H.; Koay, E. J.; Zhao, Z.; Hu, Y. Nature Biomedical Engineering 2017, 1 (0021). Duxbury, M. S.; Ito, H.; Zinner, M. J.; Ashley, S. W.; Whang, E. E. Biochemical and Biophysical Research Communications 2004, 320 (4), 1096-1102. Jazieh, K. A.; Foote, M. B.; Diaz, L. A. Seminars in Radiation Oncology 2014, 24 (2), 67-76. Ansuini, H.; Meola, A.; Gunes, Z.; Paradisi, V.; Pezzanera, M.; Acali, S.; Santini, C.; Luzzago, A.; Mori, F.; Lazzaro, D.; Ciliberto, G.; Nicosia, A.; Monica, N. L.; Vitelli, A. Journal of Oncology 2009, 2009, 1-10. Ballehaninna, U. K.; Chamberlain, R. S. Tumor Biology 2013, 34 (6), 3279-3292. Melo, S. A.; Luecke, L. B.; Kahlert, C.; Fernandez, A. F.; Gammon, S. T.; Kaye, J.; Lebleu, V. S.; Mittendorf, E. A.; Weitz, J.; Rahbari, N.; Reissfelder, C.; Pilarsky, C.; Fraga, M. F.; Piwnica-Worms, D.; Kalluri, R. Nature 2015, 523 (7559), 177-182. Roma-Rodrigues, C.; Raposo, L.; Cabral, R.; Paradinha, F.; Baptista, P.; Fernandes, A. International Journal of Molecular Sciences 2017, 18 (1), 162. Kalra, H.; Adda, C. G.; Liem, M.; Ang, C.-S.; Mechler, A.; Simpson, R. J.; Hulett, M. D.; Mathivanan, S. Proteomics 2013, 13 (22), 3354-3364. Ballehaninna, U. K.; Chamberlain, R. S. Indian Journal of Surgical Oncology 2011, 2 (2), 88-100. Pancreatic Cancer https://www.cancer.org/cancer/pancreatic-cancer.html (accessed Mar 20, 2017). Eldorado by Edgar Allan Poe | Analysis Eldorado by Edgar Allan Poe | Analysis In the poem Eldorado, poet Edgar Allan Poe delivers a fundamental message that can be understood if carefully evaluated. Poe gives the account of a knight in search of a land called Eldorado, which holds riches and fortune. After much futile searching, the knights enthusiastic quest for treasure ends in death. The foremost theme of this poem is the desire for wealth and treasure. This theme is an influence from Poes life and the relevant Gold Rush of 1849 (Coad 60). The literary devices, symbols, relevancy, and personal experiences offer a deeper meaning to the poem than what lies on the surface. Poes skillful use of these elements helps to stress the ignorant desire humans have for wealth and fortune. The poem delivers a reflective moral issue many readers can, in some way or another, relate to. Poe uses the word shadow in each of the four stanzas of the poem, each stanza consisting of six lines. The third line in each stanza is where the use of the word shadow is introduced. Though the word occurs multiple times, it has a different meaning each time. The first shadow represents a literal shadow, a casting shadow of the sun. It could also be interpreted as happiness and sadness. The second shadow represents the shadow that has overcome the knights heart after much unsuccessful searching. The third shadow represents a live figure, possibly his or maybe an angel. And the fourth shadow figuratively refers to Valley of the Shadow (21). The fact the knight has grown old and weak, and must cross Over the Mountains Of the Moon, Down the Valley of the Shadow is seen as a symbol of the knights death, relating to the Biblical valley of death (19-21). Through Poes use of the word shadow and the period in which the poem was written, readers can understand Poes message. Poe uses the shadow in each stanza to convey his message. As the meaning of the shadow changes, so do readers emotional state. As he begins the first stanza, readers see a happy, gaily, bedighted knight who is enthusiastic about going on his search for gold. This start gives readers a sense of happiness and jolt of energy. His shadow could also be a foreshadowing of future events. However, Poe begins the second stanza with the word But. This contradictory word signals a shift between the first and second stanza and also a shift in emotion. The knight has become old, disheartened, and dismayed as the shadow is used in context to signal the emotional state of the knight. This signal causes readers to suddenly have a change in emotion; readers become sympathetic towards the knight. Poe continues to elaborate on the disappointment of the knight in stanza three. The knight encounters a live or possibly imaginative figure and asks the shadow where is Eldorado, reflecting on his hopeless jo urney in which he wasted his life. This figure could possibly be an angel providing guidance, an angel of death, or even himself. As the shadow replies to the question in stanza 4, readers are left with the idea that he has come to the end of his life and has died. With the closing of the poem, the audience can relate to the pain the knight feels. In all, the repetitive shadow becomes engraved in the readers mind, helping to sway the emotions. The life of the knight also provides a moral for people to learn. Poes moral in Eldorado is not to seek for riches on earth. The only true riches are the riches one receives after death. The knight in the poem seeks for physical riches for many years without any hope, leaving him disheartened and at the end of his life. When asked where Eldorado could be, the knight was told Down the Valley of the Shadow (21). This insinuation emphasizes the main point that true riches are found in Heaven, not earth, and any riches sought on earth leads to despair and death. As suggested by The Meaning of Poes Eldorado by the John Hopkins University Press, it can be argued Poe portrayed himself as the knight (Coad 60). Poe published his poem in 1849, the same year as his death. Like the knight, Poe had sought after an accomplished life, which he failed to do during his life. He was also unstable in the last years of his life. However, the knight most probably was a reference to the many prospectors of the California Gold Rush, which took place during the time the poem was written. The poem may have been Poes warning to the many prospectors that would experience the same hardships of the knight. Poes repetition of shadow and Eldorado and use of other symbols play an important part in his poem. It helps to further stress his main point. Other such devices Poe uses to communicate to his audience is through auditory and imagery senses. Poe uses aabccb rhyme scheme in the first three stanzas and xxabba rhyme scheme in the fourth stanza of his poem . Poes creatively written stressed and unstressed poem is one way Poe remarkably appeals to the readers auditory and imagery senses. The use of this rhyme scheme creates a thumpity, thump sound when read aloud, bringing the clattering of the horses trot to life. The symbols and rhyme scheme helps to immerse the reader into the scene of the poem and drives them to continue reading until the end. Eldorado is a poem by Edgar Allan Poe that has a stressed message to readers. It tells the story of a knight who traveled for a period of his life searching for a city of gold, Eldorado. It provides a message to all readers that true riches and happiness are only acquired through Heaven after death. If one attempts to search for wealth, in hopes happiness will follow, that person will come to the end of their life saddened and in despair. Poes use of symbols, rhyme scheme, and repetition brings life to his poem, which keeps the readers entertained and helps to convey his message. The poem brings light to the life of everyone and anyone searching for happiness and wealth on earth. Thus, Eldorado is Over the Mountains Of the Moon, Down the Valley of the Shadow, Ride, boldly ride . . . If you seek for Eldorado! (19-24).

Saturday, January 18, 2020

Architecture Design, the Royal Ontario Museum

The museum is currently undergoing a major renovation and expansion project, dubbed Renaissance ROM, located at the corner of Bloor Street and Avenue Road, north of Queen’s Park and on the east side of Philosopher’s Walk in the University of Toronto. The centrepiece is the recently-opened Michael Lee-Chin Crystal, designed by architect Daniel Libeskind and Bregman + Hamann Architects; installation of exhibits in the addition will continue over a period of months. Existing galleries and buildings are also being modified. Renovated galleries in the historic buildings will reopen in stages, and all work is scheduled to be completed by 2010. The final cost of the project will be $270 million CAD. The Libeskind design, selected from among 50 entrants in an international competition, saw the award winning Terrace Galleries torn down and replaced with a Deconstructivist crystalline-form clad in 25 percent glass and 75 percent aluminium. The building is named after Michael Lee-Chin, who donated $30 million towards its construction. It houses the new main entrance to the museum, a gift shop, a restaurant (C5 Restaurant and Lounge), a cafeteria (Food Studio), seven additional galleries and Canada’s largest temporary exhibition hall in the lower level. The Crystal’s canted walls do not touch the sides of the existing heritage buildings, save for where pedestrian crossing occurs and to close the envelope between the new form and the existing walls. Although designed to conform to existing height restrictions and maintain sight lines along Bloor Street, the Crystal, at certain points, cantilevers over the setback and into the street allowance. The building’s design is similar to some of Libeskind’s other works, notably the Jewish Museum in Berlin, the London Metropolitan University Graduate Centre, and the Fredric C. Hamilton Building at the Denver Art Museum. The steel framework was manufactured and assembled by Walters Inc. of Hamilton, Ontario. The extruded anodized aluminium cladding was fabricated by Josef Gartner in Germany, the only company in the world that can produce the material. The company also provided the titanium cladding for Frank Gehry’s Guggenheim Museum in Bilbao, Spain.

Friday, January 10, 2020

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Wednesday, January 1, 2020

Essay about The Call of the Wild Versus Into the Wild

Chris McCandless and Buck serve as examples of the archetype of the wild through their experiences of leaving where they feel most comfortable and answering the call of the wild. They show that each experience is inimitable because the wild is unique to every individual. For Buck, the wild is a place outside of civilization and his dependence on man, where the external threats of nature exist and he must prove himself as a true animal with instincts for survival. In McCandless case, the place outside of civilization is actually an escape from his fears because the wild for him is in relationships, where the threat of intimacy exists and he must learn to trust others for happiness. This is because for each of us, the wild is what we†¦show more content†¦The feelings shared between them were often based on inexplicable natural impulses, characteristic of the relationship between man and beast. He went wild with happiness when Thornton touched him or spoke to him....the str ength of Bucks gaze would draw John Thorntons head around, and he would return the gaze, without speech, his heart shining out of his eyes as Bucks heart shone out (London 75). The connection that the two share is very important in Bucks transformation because it is the last thing he must surrender to complete his transformation and answer the call of the wild. John Thornton, who is unafraid of the wild, is the last thing Buck has that protects him from the hostile environment where only the strong survive (London 86). After Thornton nurses Buck back to life from his brush with starvation, Buck slowly realizes that he is ready to face the wild, where he would find his true self, not as a pet or a sled dog, and most importantly as an animal without a master. It becomes apparent that, Faithfulness and devotion, things born of fire and roof, were his; yet he retained his wildness and wiliness. He was a thing of the wild, come in from the wild to sit by John Thorntons fire, rather than a dog of soft Southland stamped with the marks of generations of civilization (London 76). Buck used Thorntons love as an escape from the wild, and depended on the comfort Thornton provided as a safeShow MoreRelatedCreation : God Vs. Nature1191 Words   |  5 Pagesquestion the explanation of God for why humans, plants, and animals exist the way they do. The work of Darwin and Wallace introduced the idea of the evolutionary theory, which changed the boundaries between humans and nature by driving people to call into question one of the fundamental ideas of the divine creation myth as written in the Bible: that humans were created by God separately from animals. Darwin and Wallace s theory of evolution broke down this boundary between human exceptionalismRead MoreWhat Are Capuchin Monkeys Are Well Known For Their Brains1309 Words   |  6 Pagesthe wild. From their unique fur colorization, their fur is white from head to shoulders while from the shoulders down there color is black. The locomotion that they use to maneuver swinging from tree to tree is by using all four li mbs and for a short period of time they can walk on two legs. Capuchin monkeys are uniquely different and surprisingly very knowledgeable at what they do in order to be able to maintain their survival based on learned and experimental behaviors. Tool Use among Wild Capuchins:Read MoreJack London : An Oyster Pirate1204 Words   |  5 Pagesshared include: his life, evolution, brutality of society, socialism, and adjustment of man against elemental ways of life (Jack London Themes and Messages) 2. Many of his works were based off experiences London had in his lifetime, such as â€Å"Call of the Wild.† London was a serious believer of Charles Darwin’s theory of evolution and the theory of survival of the fittest can be found in everything he wrote. London was also a follower of Karl Marx and his beliefs; many of these views can be seen inRead MoreEssay about Personal Narrative - My Mother, the Hippie775 Words   |  4 Pagescontact with nature that occurs (i.e., mucking around and seeing alligators in the wild). As my mother lives in Alaska, she has only been to Miami to visit me once since I moved here, and unfortunately it was within the first few months that I lived here, so I was unable to adequately provid e her with answers to her inquiries of the local plant and animal life. But now, even after only one day of class, I feel the need to call my mom and tell her all about the plants and animals I saw, and which are nativeRead MoreThe Wolf: Homo Homini Lupus811 Words   |  3 Pagesaddresses the idea that Europeans may be the savages. He says,† It is no lie to say that these men are indeed savages- by our standards; for either they must be or we must be: there is an amazing gulf between their souls and ours†(239). Montaigne calls the cannibals savages, implying that their practice and society are not comparable to those that he is acquainted with. This quotation helps to exemplify that the perception of a culture as barbaric or animal-like is dependent on the individual’s perspectiveRead MoreEssay on A Study Of Inheritable Traits In Fruit Flies1554 Words   |  7 Pages We collected the data from the crosses and analyzed them in relation to the expected results. MATERIALS AND METHODS For the monohybrid cross in this experiment, we used an F1 generation, which resulted from the mating of a male homozygous wild-type eyed fly with a female homozygous sepia eyed fly. Males and females are distinguished by differences in body shape and size. Males have a darker and rounder abdomen in comparison to females, which are more pointed. Another difference occursRead MoreA Study of Inheritable Traits in Fruit Flies1698 Words   |  7 Pagesthe next. We collected the data from the crosses and analyzed them in relation to the expected results. MATERIALS AND METHODS For the monohybrid cross in this experiment, we used an F1 generation, which resulted from the mating of a male homozygous wild-type eyed fly with a female homozygous sepia eyed fly. Males and females are distinguished by differences in body shape and size. Males have a darker and rounder abdomen in comparison to females, which are more pointed. Another difference occursRead MoreWhy Humans Develop Their Psychological Attributes Based On Genetics ( Nature ) Or Their Environment1085 Words   |  5 Pagesferal child was raised by wild animals such as Victor, the wild boy of Aveyron it is inevitable for the child s nurture to be superior to that of its nature(The development of children, 7th edition, Lightfoot, and Cole).Feral children are considered a debate between nature and nurture because the child recovered from the wild, mimics the environment and the characteristics of the wild animal that raised the child while applying the wisdom it gained surviving in the wild, lacking social intelligenceRead MoreResearch Paper On Trading Volume1034 Words   |  5 Pagesmore capitalization and better fundamentals overall (but not always!). The majority of the penny stocks do not trade on the big exchanges. Instead, they trade in what I like to call Wild West of the stock market. The Wild West consists of the bulletin boards (OTCBB) and the pink sheets. While the OTCBB is part of the WIld West, it is a tamer portion. Most people dont realize but the OTCBB is actually owned by the NASDEQ and they do have rules and requirements for listing. Where you get the mostRead More Henrik Ibsen Essay2054 Words   |  9 Pages In the plays Ghosts, An Enemy of the People, and Wild ducks by Henrik Ibsen there are many similar themes, which become evident to the reader. A theme, which is consistant though out these plays, is the opposing values of the Ideal and the Real. The views of the idealist versus the realists make for many duels between the two personalities. The theme of idealism versus realism is also dealt with in the play The Wild Duck. Gregers Werle has avoided his father, whom he detests, by spending fifteen